Interleukin-8 reduces post-surgical lymphedema formation by promoting lymphatic vessel regeneration
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چکیده
منابع مشابه
Adiponectin‐Mediated Modulation of Lymphatic Vessel Formation and Lymphedema
BACKGROUND Obesity is linked with an increased risk of lymphedema, which is a serious clinical problem. Adiponectin is a circulating adipokine that is down-regulated in obese states. We investigated the effects of adiponectin on lymphatic vessel formation in a model of lymphedema and dissected its mechanisms. METHODS AND RESULTS A mouse model of lymphedema was created via ablation of tail sur...
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The lymphatic system is essential for the maintenance of tissue fluid homeostasis, gastrointestinal lipid absorption, and immune trafficking. Whereas lymphatic regeneration occurs physiologically in wound healing and tissue repair, pathological lymphangiogenesis has been implicated in a number of chronic diseases such as lymphedema, atherosclerosis, and cancer. Insight into the regulatory mecha...
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ژورنال
عنوان ژورنال: Angiogenesis
سال: 2012
ISSN: 0969-6970,1573-7209
DOI: 10.1007/s10456-012-9297-6